Baishideng Publishing Group

Yang Y, Song WJ, Zhang JJ. Ras homolog enriched in brain 1 regulates β cell mass and β cell function via mTORC1/AMPK/Notch1 pathways. World J Diabetes 2025; 16(6): 104973

"Thank you for accepting our paper. We are looking forward to publishing it soon. In the past, we had some trouble submitting our papers ..." [Read more]

"Thank you for accepting our paper. We are looking forward to publishing it soon. In the past, we had some trouble submitting our papers to WJGE, but now that we are used to it, we were able to submit smoothly this time. We are satisfied with the submission and peer review system. Best regards, " [Collapse]

Nishizawa T, Toyoshima O, Yoshida S, Takahashi Y, Nakagawa H, Mizutani H, Kataoka Y, Kanazawa T, Ebinuma H, Hata K. Advantages of new generation colonoscopes on adenoma detection: A propensity-score matching study. World J Gastrointest Endosc 2025; 17(6): 108146

"The work of reviewing and editing the article, the work of the editors of the World Journal of Gastroenterology makes the most pleasant ..." [Read more]

"The work of reviewing and editing the article, the work of the editors of the World Journal of Gastroenterology makes the most pleasant impression and is characterized by extremely high punctuality and professionalism. I wish the journal to continue to maintain such an attitude to work. We are very pleased to publish in your journal. " [Collapse]

Tsukanov VV, Vasyutin AV, Kasparov EV, Tonkikh JL. Is the use of artificial intelligence the main stage for detecting polyps during colonoscopy? World J Gastroenterol 2025; 31(22): 106500

"Thank you very much for the prompt and efficient review and publication process of our manuscript. I sincerely appreciate the ..." [Read more]

"Thank you very much for the prompt and efficient review and publication process of our manuscript. I sincerely appreciate the professionalism, clarity, and timely communication demonstrated by the editorial team throughout each step. The entire experience was smooth, well-organized, and encouraging. I am genuinely grateful for your continued support and dedication. " [Collapse]

Suh JW, Jo JW, Park DG. Long-term survival of a patient with colorectal cancer with peritoneal carcinomatosis and low completeness of cytoreduction score: A case report. World J Gastrointest Oncol 2025; 17(6): 106846

"We sincerely appreciate the exceptional professionalism and efficiency of the World Journal of Diabetes editorial team throughout ..." [Read more]

"We sincerely appreciate the exceptional professionalism and efficiency of the World Journal of Diabetes editorial team throughout the publication process. The peer reviewers provided insightful and constructive feedback, significantly enhancing our manuscript’s quality. The editors and staff demonstrated remarkable responsiveness, clear communication, and dedication to academic excellence. The F6Publishing platform was user-friendly, streamlining submission and tracking. This experience has been highly positive, and we look forward to future collaborations. " [Collapse]

Tang D, Wang CF, Wang J, Jing XT, Ma J. Mechanism of the epidermal growth factor receptor in promoting endothelial cell dysfunction in gestational diabetes mellitus. World J Diabetes 2025; 16(6): 105173

"As an author who has recently submitted a manuscript to the World Journal of Gastroenterology, I have had the opportunity to experience ..." [Read more]

"As an author who has recently submitted a manuscript to the World Journal of Gastroenterology, I have had the opportunity to experience firsthand the thorough and professional review process that this journal employs. Throughout the entire submission and review process, I was deeply impressed by the efficiency and meticulousness of the editorial team and the expertise of the reviewers. From the moment of submission, the editorial staff were highly responsive. They promptly acknowledged receipt of the manuscript and provided clear instructions on the next steps. The initial screening process was swift, and I appreciated the thoroughness with which they checked for adherence to the journal's guidelines. This attention to detail set a high standard for the rest of the process. The peer review process was particularly noteworthy. The reviewers assigned to my manuscript were clearly experts in the field of gastroenterology. Their comments were not only insightful but also constructive. They provided detailed feedback on the methodology, results, and discussion sections, highlighting both strengths and areas for improvement. Their suggestions were specific and actionable, which made the revision process much more manageable. It was evident that they had invested significant time and effort into understanding the nuances of my research. The communication between the editorial team and the authors was seamless. I received timely updates on the status of the review and was given ample opportunity to address the reviewers' concerns. The editor's decision was fair and well-reasoned, based on the comprehensive feedback from the reviewers. Even though my manuscript required major revisions, I felt encouraged and supported throughout the process. Overall, my experience with the World Journal of Gastroenterology has been highly positive. The rigorous review process ensures that only high-quality research is published, which benefits the entire academic community. The dedication of the editorial team and the expertise of the reviewers make this journal a valuable platform for researchers in the field of gastroenterology. I would highly recommend submitting to this journal and look forward to the possibility of publishing with them again in the future. " [Collapse]

Chen CR, Jin HL, Xu QJ, Yuan YL, Hu ZH, Liu Y, Lei HK. Development and validation of a nomogram for predicting postoperative venous thromboembolism risk in patients with hepatocellular carcinoma. World J Gastrointest Oncol 2025; 17(6): 105790

"The overall work is well done. But there are two parts I want to put some suggestions: 1). the period of publication was taken too ..." [Read more]

"The overall work is well done. But there are two parts I want to put some suggestions: 1). the period of publication was taken too longer time, for our manuscript, it'a take more then 200 days, the time should be reduced, and 2). the whole process was designed too complicated, it's also can be optimized. " [Collapse]

Gao L, Lai JS, Chen H, Qian LX, Hong WJ, Li LC. Mechanism of trypsin-mediated differentiation of pancreatic progenitor cells into functional islet-like clusters. World J Diabetes 2025; 16(6): 102727

"I have experienced some challenges with email communication in certain Baishideng Publishing Group journals. For example, I have been ..." [Read more]

"I have experienced some challenges with email communication in certain Baishideng Publishing Group journals. For example, I have been unable to read some emails properly, have not received others, and in some cases, have not received responses to my inquiries. I believe that improving email communication would significantly enhance the efficiency and clarity of the publication process. " [Collapse]

Antonini F, Donnarumma D, Buono T. Is endoscopic retrograde cholangiopancreatography safe for centenarians? World J Gastrointest Endosc 2025; 17(6): 106142

"Thank you for the time and effort you have put into reviewing the manuscript. In the future, it would be helpful to have a somewhat ..." [Read more]

"Thank you for the time and effort you have put into reviewing the manuscript. In the future, it would be helpful to have a somewhat clearer idea in advance of the various steps that will take place during the process after the peer review has been complete. We are grateful for the attention to detail, also in terms of accompany documents, etc. " [Collapse]

Kruis W, Jessen P, Morgenstern J, Reimers B, Müller-Grage N, Bokemeyer B. Shared decision-making improves adherence to mesalamine in ulcerative colitis: A prospective, multicenter, non-interventional cohort study in Germany. World J Gastroenterol 2025; 31(22): 101915

"We would like to thank the editorial team and reviewers for their time, valuable feedback, and professional support. We have carefully ..." [Read more]

"We would like to thank the editorial team and reviewers for their time, valuable feedback, and professional support. We have carefully reviewed all the requirements and have revised the manuscript accordingly. We are also grateful for the opportunity to submit our work to your esteemed journal. We are satisfied with the entire submission and editorial process and appreciate the clarity and efficiency of the workflow. Thank you for your consideration. Sincerely, " [Collapse]

Zeynelgil E, Duzkopru Y, Kocanoglu A, Karakaya S. Prognostic value of hemoglobin-to-red cell distribution width ratio and inflammation markers in colorectal cancer. World J Gastrointest Oncol 2025; 17(6): 106603

"I must say, without exaggeration, that this is one of the most satisfying journals I have submitted to thus far. The review process ..." [Read more]

"I must say, without exaggeration, that this is one of the most satisfying journals I have submitted to thus far. The review process is incredibly fast, the feedback is professional, and the editorial efficiency is exceptional. Emails and responses are handled swiftly, making the overall experience highly efficient. I have recommended this journal to several colleagues and classmates, and they have all expressed their satisfaction. I look forward to the opportunity to publish more articles in this series of journals in the future. " [Collapse]

Wang L, Wang MH, Yuan YH, Xu RZ, Bai L, Wang MZ. Identification and validation of extracellular matrix-related genes in the progression of gastric cancer with intestinal metaplasia. World J Gastrointest Oncol 2025; 17(6): 105160

"World Journal of Gastrointestinal Oncology, as a leading authoritative journal in the field of gastrointestinal oncology, has earned ..." [Read more]

"World Journal of Gastrointestinal Oncology, as a leading authoritative journal in the field of gastrointestinal oncology, has earned high recognition from the academic community through its outstanding scholarly standards and professional publishing services. The journal maintains rigorous quality control of manuscripts through its editorial board composed of internationally renowned experts, while its professional peer-review system provides constructive feedback that not only ensures the academic value of published papers but also effectively enhances researchers' academic capabilities. Featuring an efficient publication process, a user-friendly online submission system, and a responsive editorial team, the journal offers authors worldwide an exceptional submission experience. With its rigorous academic approach, streamlined publishing operations, and comprehensive author services, World Journal of Gastrointestinal Oncology has become the preferred platform for scholarly publication among researchers in gastrointestinal oncology, making significant contributions to advancing academic exchange and scientific progress in this field. " [Collapse]

Jia C, Lang QF, Yin ZJ, Sun J, Meng QH, Pei TM. Role, mechanism, and application of N6-methyladenosine in hepatobiliary carcinoma. World J Gastrointest Oncol 2025; 17(6): 105140

"Thank you for providing the opportunity to participate in this survey. Overall, the submission process is clear, the system operates ..." [Read more]

"Thank you for providing the opportunity to participate in this survey. Overall, the submission process is clear, the system operates smoothly, and the review speed is within a reasonable timeframe. I hope that in the future, the quality of reviewer feedback can be further improved, and communication efficiency between authors and the editorial team can be strengthened. I look forward to seeing continued improvements in service quality, providing a better submission and publishing platform for the research community. " [Collapse]

Shih YH, Yang CY, Lung CC. Long-term risk of diabetes following hypertensive disorders of pregnancy: A retrospective cohort study. World J Diabetes 2025; 16(6): 105080

"The magazine consistently delivers content of intellectual depth and contemporary relevance through rigorous research and diverse ..." [Read more]

"The magazine consistently delivers content of intellectual depth and contemporary relevance through rigorous research and diverse perspectives. From cutting-edge industry trends to socio-cultural issues, each article transforms professional knowledge into a relatable reading experience via solid arguments and vivid storytelling, serving as a premium medium that bridges rational thinking and emotional resonance. " [Collapse]

Wan LH, Mao BJ, Wang B. Relationship between skeletal muscle mass and prognosis in patients with liver cancer receiving targeted therapy: A meta-analysis. World J Clin Oncol 2025; 16(5): 102611

"Overall, I am satisfied with the publication timeline, particularly during the peer review stage. The following suggestions are ..." [Read more]

"Overall, I am satisfied with the publication timeline, particularly during the peer review stage. The following suggestions are provided for your consideration: 1. Expedite the process from acceptance to final publication. The interval between payment of fees and formal publication took over two months, which seems protracted. Accelerating this stage would be beneficial. 2. Could the system clearly indicate that payment is required only after manuscript acceptance? " [Collapse]

Wei JR, Ouyang YN, Tang MT, Yuan JZ, Wang PL, Jiang LH, Wu LC. Charged multivesicular body protein 7 was identified as a prognostic biomarker correlated with metastasis in colorectal cancer. World J Gastrointest Oncol 2025; 17(6): 105967

"The structure of the submission system is optimized.The entire processing of the manuscript was very convenient.We would like to ..." [Read more]

"The structure of the submission system is optimized.The entire processing of the manuscript was very convenient.We would like to express our gratitude to all reviewers and editors for their support of our manuscript.And I will continue to submit my papers to this journal in the future.Thank you once again for your assistance and support! " [Collapse]

Gong KR, Zheng ZL, Li GF, Chen JM. Endoscopic retrograde cholangiopancreatography treatment of cholangitis stone in a patient with total situs inversus: A case report. World J Gastrointest Endosc 2025; 17(6): 106347

"The structure of the submission system is optimized, the editing work is serious and responsible, the manuscript is replied in time, ..." [Read more]

"The structure of the submission system is optimized, the editing work is serious and responsible, the manuscript is replied in time, the manuscript is carefully reviewed and processed, and from the perspective of editing, the language and expression are optimized to provide readability of the article.Thank you very much.Best regards. " [Collapse]

Xu J, Li SX, Liu D, Chen LX, Chen X. Diagnostic value of serum pepsinogen, gastrin, and carbohydrate antigens in gastric ulcer and gastric cancer. World J Gastrointest Oncol 2025; 17(6): 105931

"I would like to sincerely thank the editorial board and the reviewers for their fair and constructive evaluation of our manuscript. ..." [Read more]

"I would like to sincerely thank the editorial board and the reviewers for their fair and constructive evaluation of our manuscript. Their insightful comments and suggestions significantly improved the quality and clarity of our work. I truly appreciate the collaborative spirit of the process and look forward to future opportunities for scholarly collaboration and continued engagement with the journal. " [Collapse]

Al Madhoun A. Epigenetics and diabetic wound healing: Wilms tumor 1-associated protein as a therapeutic target. World J Diabetes 2025; 16(6): 105615

"I appreciate your help. The journal editors responded to my inquiries very quickly and facilitated the process. The reviewers of this ..." [Read more]

"I appreciate your help. The journal editors responded to my inquiries very quickly and facilitated the process. The reviewers of this journal evaluated the manuscript very fairly and the quality of the manuscript improved during the revision process. I am grateful to the reviewers and editors of this journal. I plan to continue to submit manuscripts to this journal in the future. " [Collapse]

Byeon H. Future of diabetic foot risk: Unveiling predictive continuous glucose monitoring biomarkers. World J Diabetes 2025; 16(6): 107006

"I appreciate your help. The journal editors responded to my inquiries very quickly and facilitated the process. The reviewers of this ..." [Read more]

Byeon H. Beyond association: Examining overweight as a mediator in the link between depression and diabetes. World J Diabetes 2025; 16(6): 107071

18845 items Read more >>

Article Quality Tracking-Peer-Review

"The ethical approval meets requirements. The study obtained approval (CE24431B) from Taichung Veterans General Hospital. The methods ..." [Read more]

"The ethical approval meets requirements. The study obtained approval (CE24431B) from Taichung Veterans General Hospital. The methods are effective and can be repeated by fellow researchers. They conducted a robust retrospective cohort using the TriNetX database, which harmonizes EHR data across 80 U.S. healthcare organizations. Besides, the inclusion and exclusion criteria are clear. The results of this study are authentic, reliable and validate the initial hypothesis. The tables, graphs, and figures were constructed and annotated well. But one mistake was presented in Table 3. Gestational hypertension HR typo ("HR: 1.936(1.844,0.033)" – "0.033" likely should be "2.033"). The biostatistics data was generally right. However, more details of PSM and some sensitivity analyses (e.g., competing risks for mortality) are suggested to be added. Authors have cited key references to support the pathophysiological mechanisms and prior epidemiological relationship, as well as some recent references. I suggest adding recent reviews on PIH-related metabolic dysfunction. The language is generally clear, concise, and logically structed." [Collapse]

Shih YH, Yang CY, Lung CC. Long-term risk of diabetes following hypertensive disorders of pregnancy: A retrospective cohort study. World J Diabetes 2025; 16(6): 105080

"This was prospective study investigating factors that could potentially influence mesalamine adherence in patients with ulcerative ..." [Read more]

"This was prospective study investigating factors that could potentially influence mesalamine adherence in patients with ulcerative colitis (UC), highlighting the impact of shared-decision-making on treatment outcomes. Basically, the results of the study indicate that when patients are involved in choosing their medication formulation, particularly granules, their adherence significantly improves, leading to better disease activity control. While acknowledging some limitations, such as reliance on self-reported adherence and potential participant dropout, the findings emphasize the importance of patient-centered care and accommodating individual preferences in long-term UC management. Ultimately, the study suggests that integrating shared-decision-making into routine gastroenterology practice might enhance adherence and overall outcomes. Regarding specific aspects: The ethical approval process appears to meet standard requirements based on the information provided. The study was reviewed and approved by the Ethics Committee of the North Rhine Chamber of Physicians, and registered on ClinicalTrials.gov. All study participants provided signed informed consent before study enrollment. Patient data were entered into an online electronic database using the double data entry method. The experimental method is described with sufficient detail to assess its effectiveness and potential for reproducibility. Basically, this was a 12-month, prospective, multicenter, non-interventional cohort study conducted at 113 specialty gastroenterology practices in Germany. The study design allowed for the collection of real-world data without formal interventions, which is highlighted as a strength. Eligibility criteria were clearly defined, and the inclusion of patients initiating or re-initiating mesalamine treatment in routine practice across Germany enhances the real-world applicability of findings. Decisions about diagnostic procedures and treatment were made by the treating physician according to patients’ clinical needs and independently of the study, ensuring routine clinical practice was observed. Disease activity was assessed using the partial Mayo score, with scores ranging from 0 to 9. Patient knowledge of UC was assessed using a self-developed, patient-administered questionnaire with two parts: self-rating and nine yes/no questions grouped into poor, moderate, or good/very good categories. Adherence was assessed using a self-developed, patient-administered questionnaire with a visual analogue scale (VAS). The reliance on a self-developed, self-reported VAS for adherence is noted as a potential limitation as it tends to overestimate adherence, though it is considered a simple and realistic measurement often used in practice. Patient involvement in treatment decision-making was not directly measured but inferred as a "proxy": instances where patients received their preferred mesalamine formulation were considered cases of shared decision-making. This is explicitly stated as an oversimplification and a limitation of the study. The authors provide information on the biostatistical methods used and present numerical results. The description of biostatistical methods and reported results appears to be correctly conducted. The results are presented clearly, supporting the study's aims and partially validating its hypothesis. However, the authors acknowledge that if all lost-to-follow-up patients are assumed to have suboptimal adherence, the rates drop dramatically at Visit 3, aligning more with previous literature. This demonstrates authenticity in acknowledging potential biases. Patient knowledge of UC (self-estimated or objectively measured) showed no significant association with adherence. Patients reporting good adherence experienced significant improvements in disease activity over 12 months. Patients who received their preferred formulation experienced continuous improvement in pMayo scores over 12 months. The figures, tables, and the diagram are clear and provide important information. The references provided suggest a reasonable approach to literature review on the subject., presenting relevant sources. There is no direct evidence to suggest self-citation, omission, mis-citation, or over-citation. The language used in the article is generally clear, concise, and grammatically correct. The study explicitly details its limitations in the "Strengths and limitations of the study" section. " [Collapse]

"Authors studied a clinically important yet underexplored aspect of young-onset type 2 diabetes mellitus (T2DM): the association between ..." [Read more]

"Authors studied a clinically important yet underexplored aspect of young-onset type 2 diabetes mellitus (T2DM): the association between vitamin D (VitD) status and apolipoprotein A1 (apoA1); a major component of HDL cholesterol with established cardioprotective properties. The study is one of the first to evaluate the relationship between VitD and apoA1 specifically in young-onset T2DM, a population at heightened risk for early cardiovascular morbidity and mortality. Since apoA1 plays a critical role in reverse cholesterol transport and HDL function, its association with VitD status provides a potential mechanistic link between VitD deficiency and increased cardiovascular risk in young-onset T2DM patients. However, the thresholds for “severe” VitD deficiency and the proportion of individuals in each deficiency category could be more clearly reported for better clinical applicability." [Collapse]

Hu Y, Shao LN, Zheng J, Zhang XM, Song YX, Xing YB. Vitamin D deficiency is associated with apolipoprotein A1 levels in patients with young-onset type 2 diabetes mellitus. World J Diabetes 2025; 16(6): 105558

"Li et al's work is a narrative review article focusing on the emerging role of ferroptosis in the pathogenesis of diabetic ..." [Read more]

"Li et al's work is a narrative review article focusing on the emerging role of ferroptosis in the pathogenesis of diabetic cardiomyopathy (DCM) and its potential as a therapeutic target. Ferroptosis inhibitors (e.g., ferrostatin-1, liproxstatin-1, and iron chelators) have demonstrated protection against lipid ROS accumulation and reduction of cardiac injury and fibrosis in preclinical models. Ferroptosis is a cutting-edge area of research with growing relevance in diabetic complications. The review links molecular pathways (GPX4, ACSL4, iron metabolism) to clinical manifestations of DCM. Highlights ferroptosis inhibition as a potentially novel and actionable intervention for a currently untreatable condition. Justifies the need for alternative treatments beyond glycemic control in DCM. These agents are being explored for iron overload cardiomyopathies and may be repurposed or tailored for DCM." [Collapse]

Li GZ, Liu JY, Zhou H. Ferroptosis: A novel therapeutic target for diabetic cardiomyopathy. World J Diabetes 2025; 16(6): 104665

"Authors studied an important limitation in diabetes management: the inadequacy of HbA1c in fully capturing glycemic control, ..." [Read more]

"Authors studied an important limitation in diabetes management: the inadequacy of HbA1c in fully capturing glycemic control, particularly in patients with type 1 diabetes (T1D). The authors introduce and validate the Glycemia Risk Index (GRI) as a more holistic tool by integrating data from continuous glucose monitoring (CGM). Study results indicated that GRI showed strong inverse correlation with time in range (TIR) (r = -0.90) and positive correlations with time below range (TBR), time above range, and glycemic variability (CV)—metrics that HbA1c poorly reflects. Each 1% increase in TBR or CV substantially raises the GRI, highlighting its sensitivity to dangerous glycemic patterns that HbA1c alone would miss. While the GRI is statistically elegant, its ease of use and interpretation by patients and non-specialist clinicians remain unexplored. User-friendliness is critical for widespread adoption." [Collapse]

He BB, Liu ZZ, Xu RY, Fan L, Guo R, Deng C, Xie YT, Zhou ZG, Li X. Glycated hemoglobin is not enough: The role of glycemia risk index for glycemic control assessment in type 1 diabetes. World J Diabetes 2025; 16(6): 104024

"Authors studied an under-researched probiotic, Acetobacter pasteurianus, linking it with diabetes treatment via lipid metabolites, ..." [Read more]

"Authors studied an under-researched probiotic, Acetobacter pasteurianus, linking it with diabetes treatment via lipid metabolites, which is both innovative and timely given the rising interest in functional microbiota-derived therapeutics. The findings lay the groundwork for developing next-generation functional probiotics or postbiotics focused on metabolic diseases, particularly type 2 diabetes. While CoQ9 and OA were identified as hypoglycemic agents in the work, their precise molecular mechanisms of action (e.g., insulin sensitization, beta-cell preservation, or anti-inflammatory effects) remain unexplored sufficiently. No adequate data on signaling pathways (e.g., AMPK, PI3K/Akt) is included, which would strengthen the findings. " [Collapse]

Xu WY, Zhou WT, Luo JZ, Jiang YY, Zhang K, Zhang SY, Liu PS, Wei HY, Huang YQ. Lipid metabolism of Acetobacter pasteurianus and its main components with hypoglycemic effects. World J Diabetes 2025; 16(6): 103370

"None Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according ..." [Read more]

"None Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according to above listed criteria. Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according to above listed criteria Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according to above listed criteria" [Collapse]

Sun M, Yu J, Zhou JW, Ye M, Ye F, Ding M. Can ChatGPT and DeepSeek help cancer patients: A comparative study of artificial intelligence models in clinical decision support. Artif Intell Cancer 2025; 6(1): 106356

"Thanks for your interesting article. I think some points in this article should be considered. The paper provides MAILE primarily ..." [Read more]

"Thanks for your interesting article. I think some points in this article should be considered. The paper provides MAILE primarily narrative and theoretical foundations, much of the corroborative evidence coming from studies on generic isometric or core stabilization exercises. Although the authors themselves point out that direct empirical proof of MAILE is limited, no randomized controlled trials are available to contrast it with other core stabilization protocols. It is difficult to determine whether MAILE has any real clinical advantage or if it is simply a re-packaging of what is currently done, thus, in the lack of such comparisons. Additionally, besides subjective outcome measures like pain scales and questionnaires, objective physiological indicators like electromyography, motion analysis, or ultrasound imaging are desperately required in order to confirm that MAILE actually activates the assumed musculature as hypothesized. Identification of predictors of successful response to MAILE is another area that would benefit from more light. While the correlations reported (e.g., aberrant movement patterns, postpartum status, or positive Trendelenburg sign) are logical, they appear more based on the overall rehabilitation literature rather than specifically proven for MAILE. " [Collapse]

Syed Y, Hassan MA, Kalayil RM, Othman OA, Mekkodathil A, El-Menyar A. Promising technique for managing nonspecific chronic low back pain using multi angular isometric lumbar exercise. World J Orthop 2025; 16(5): 104425

"AI is usefull a lot in many fields. ARLD is common in many countries with cirrhosis complication. The article with new idea has ..." [Read more]

"AI is usefull a lot in many fields. ARLD is common in many countries with cirrhosis complication. The article with new idea has shown that using AI in ARLD management is very effective. Hopefully in the future many hospitals and medical centers will use AI in ARLD management to demonstrate effectiveness. " [Collapse]

Chen ML, Jiao Y, Fan YH, Liu YH. Artificial intelligence for early prediction of alcohol-related liver disease: Advances, challenges, and clinical applications. Artif Intell Gastroenterol 2025; 6(1): 107193

"The benefits of PRF in regulating innate immunity and encouraging wound healing have been covered in this editorial. PRF is a possible ..." [Read more]

"The benefits of PRF in regulating innate immunity and encouraging wound healing have been covered in this editorial. PRF is a possible treatment strategy for improved wound healing. It is a useful tool in therapeutic settings because of its ability to effectively promote tissue regeneration and modify innate immunity. PRF has the potential to greatly enhance patient outcomes and lessen the burden related to wound care as long as research into its processes and uses is conducted. The authors supported their manuscript by one figure and one table." [Collapse]

Mohammadi S. Innate immunity and wound repair: The platelet-rich fibrin advantage. World J Biol Chem 2025; 16(2): 107195

"In this manuscript, the authors provided a lengthy conclusion. They found that, while CQ and HCQ have shown promise in the treatment ..." [Read more]

"In this manuscript, the authors provided a lengthy conclusion. They found that, while CQ and HCQ have shown promise in the treatment of autoimmune diseases, there are several concerns and disputes surrounding their use. Although these drugs can help cure autoimmune illnesses, their use must be carefully considered in light of the benefits and drawbacks. The authors also stated that more study is needed to fully understand the therapeutic potential of CQ and HCQ in autoimmune diseases, maximize its use in clinical practice, and develop safer and more efficient treatments. In addition, the authors showed two nice figures." [Collapse]

Al-Hamadani M, Darweesh M, Mohammadi S, Al-Harrasi A. Chloroquine and hydroxychloroquine: Immunomodulatory effects in autoimmune diseases. World J Biol Chem 2025; 16(2): 107042

"In an effort to transform the treatment of Parkinson's disease and enhance patient outcomes, this review addressed preclinical ..." [Read more]

"In an effort to transform the treatment of Parkinson's disease and enhance patient outcomes, this review addressed preclinical achievements, long-term safety issues, and ethical considerations while highlighting the importance of stem cell therapy in neuroregeneration. Figures 1 and 2 are strong highlights in this manuscript, since Figure 1 depicts the classification of stem cells. As a result, this publication provided fundamental information regarding different types of stem cells and their applications in therapy." [Collapse]

Mokhtari YG, Varnava I, Kyrgiannis K, Ampatsidou V, Giakoumettis D. Stem cell therapy for Parkinson’s disease: A new hope for neural regeneration. World J Biol Chem 2025; 16(2): 106850

"In recent years, to enhance the diagnostic capability of colonoscopy in detecting polyps in the large intestine, tiny ones, various ..." [Read more]

"In recent years, to enhance the diagnostic capability of colonoscopy in detecting polyps in the large intestine, tiny ones, various computer-aided detection (CADe) systems have been increasingly utilized to improve the diagnostic accuracy of colonoscopy. In the study in question, the authors investigated precisely this possibility of CADe by conducting a meta-analysis of five relevant studies involving 1,624 examinees. They found that the adenoma missing rate was significantly lower in the group that underwent CADe compared to the group that underwent routine colonoscopy for small neoplasms. Interestingly, although the overall adenoma detection rate was not different between the two groups, it was higher in the group that underwent CADe during the first examination, suggesting that CADe significantly reduces the adenoma missing rate and polyp missing rate while improving the adenoma detection rate during the initial passage of the endoscope, thus demonstrating its potential to enhance the performance of colonoscopy. In recent years, we have witnessed the explosive growth and integration of artificial intelligence (AI) into clinical practice. It has been increasingly incorporated into clinical practice as it improves the detection of small and advanced colonic adenomas. The existing data strongly support the clinical application of AI in colonoscopy, as it significantly improves the diagnostic accuracy of endoscopy while reducing the endoscopic workload. However, over the next few years, the impact of AI applications is expected to be determined with precision, not only in the field of endoscopy but also in other areas of medical science, concerning not only gastroenterologists but also the effectiveness of daily therapeutic interventions." [Collapse]

Wang SY, Gao JC, Wu SD. Artificial intelligence for reducing missed detection of adenomas and polyps in colonoscopy: A systematic review and meta-analysis. World J Gastroenterol 2025; 31(21): 105753

"The healthy volunteers and the case groups should also be checked for conditions that would alter gut microbime including bacterial ..." [Read more]

"The healthy volunteers and the case groups should also be checked for conditions that would alter gut microbime including bacterial overgrowth syndrome. This is a large entity that consists of GI motility disorders, anatomical anomalies and so on. There are large body of evidence regarding the role of bacterial overgrowth syndrome in progression of chronic liver disease. The enterance of bacterial endotoxins through portal vein as a result of leaky gut is another important issue that should be addressed in the methodology." [Collapse]

Ma C, Yang J, Fu XN, Luo JY, Liu P, Zeng XL, Li XY, Zhang SL, Zheng S. Microbial characteristics of gut microbiome dysbiosis in patients with chronic liver disease. World J Hepatol 2025; 17(5): 106124

"A well desined study in the field of biliary stricture management. Further researches are needed to identify if stent placemnet would ..." [Read more]

"A well desined study in the field of biliary stricture management. Further researches are needed to identify if stent placemnet would have added value to biliary dilation alone. It seemes that percutaneous approach might be more feasible in proximal strictures than the distal ones. Moreover, in ishemia induced strictures, timely diagnosis and appropriate intervention might be a key preventive management." [Collapse]

Trifonov S, Kovalenko Y, Gurmikov B, Varava A, Vodeiko V, Pakhtushkin E, Vishnevsky V, Zharikov Y. Reconstructive surgery and percutaneous balloon dilation for the treatment of benign biliary strictures: A retrospective study. World J Hepatol 2025; 17(5): 104646

"Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is an effective and minimally invasive alternative treatment for gastric outlet ..." [Read more]

"Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is an effective and minimally invasive alternative treatment for gastric outlet obstruction. Compared with conventional treatments such as duodenal stent placement and surgical gastrojejunostomy, EUS-GE has comparable technical and clinical success rates, with the advantages of longer patency, fewer adverse events, and lower reintervention rates. This technique is applicable not only to malignant obstruction, but also to complex pathologies such as benign lesions and afferent loop syndrome, and is a promising treatment that allows early recovery and resumption of oral intake, which is crucial for oncological patients. This review explained this point." [Collapse]

Karagyozov PI, Kavrakov D, Shumka N. Endoscopic ultrasound-guided gastroenterostomy: The new standard treatment of gastric outlet obstruction. Artif Intell Gastrointest Endosc 2025; 6(2): 106600

"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

"The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

Zhong XY, Liang ZJ, Lan ML, Xu XG, Yuan L, Zeng JX. Acinar cystic transformation of the pancreas: A rare case report. World J Clin Cases 2025; 13(23): 107096

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Maity R, Rathna RB, Dhali A, Fernandes N, Biswas J, Kapoor GS, Dhali GK. Ulcerated benign jejunal gastrointestinal stromal tumor causing gastrointestinal bleeding: A case report. World J Clin Cases 2025; 12(23): 106140

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Cicek E, Karatepe YK, Kantarcı TR, Sahin TT. Demanding sleeve gastrectomy procedure in a patient with severe intraabdominal adhesions: A case report and review of the literature. World J Clin Cases 2025; 12(23): 104807

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 2266

Peer-reviewers: 31672

Manuscripts received today: 14

Manuscript reviews today: 58

Unhandled manuscripts today: 153

Active peer-reviewers today: 1980

Reviewer acceptance today: 104

Reviewer refusals today: 91

Total accepted manuscripts: 36458

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Total submissions: 34679